منابع مشابه
Alternating hemiplegia of childhood: new diagnostic options.
A syndrome of alternating hemiplegia of childhood (AHC) is a rare disorder first presented in 1971. AHC is characterized by transient episodes of hemiplegia affecting either one or both sides of the body. Age of onset is before 18 months and the common earliest manifestations are dystonic or tonic attacks and nystagmus. Hemiplegic episodes last minutes to days and the frequency and duration ten...
متن کاملChild neurology: alternating hemiplegia of childhood.
Jeffrey R. Tenney, MD, PhD Mark B. Schapiro, MD Alternating hemiplegia of childhood (AHC) is a rare disorder characterized by recurrent attacks of hemiplegia affecting either side of the body, abnormalities of ocular movement, movement disorders, and progressive developmental delay. Children with AHC often have a delay in diagnosis or are misdiagnosed. A broad differential diagnosis is necessar...
متن کاملA functional correlate of severity in alternating hemiplegia of childhood.
OBJECTIVE Mutations in ATP1A3, the gene that encodes the α3 subunit of the Na(+)/K(+) ATPase, are the primary cause of alternating hemiplegia of childhood (AHC). Correlations between different mutations and AHC severity were recently reported, with E815K identified in severe and D801N and G947R in milder cases. This study aims to explore the molecular pathological mechanisms in AHC and to ident...
متن کاملChild neurology: benign nocturnal alternating hemiplegia of childhood.
Laetitia J.J.C. WagenerSchimmel, MD Joost Nicolai, MD, PhD Alternating hemiplegia of childhood (AHC) is a disorder of recurrent hemiplegia beginning before age 18 months and is associated with dystonia, nystagmus, and progressive cognitive and motor impairment. This disorder was first recognized by Verret and Steele1 in 1971. Benign nocturnal alternating hemiplegia of childhood, which differs f...
متن کاملThe treatment and management of alternating hemiplegia of childhood.
Alternating hemiplegia of childhood has many factors that make it difficult to manage. These include its rarity of about one case per million, the variability of the manifestations, with seven characteristic features, and the potential for disabilities and acute, often severe, episodes in a disease that is of uncertain cause and for which treatment evidence is sparse. An integrated multidiscipl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1996
ISSN: 0022-3050
DOI: 10.1136/jnnp.60.4.466